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The SN1cB (conjugate base) mechanism describes the pathway by which many metal amine complexes undergo substitution, that is ligand exchange. Typically, the reaction entails reaction of a polyamino metal halide with aqueous base to give the corresponding polyamine metal hydroxide:〔G. L. Miessler and D. A. Tarr “Inorganic Chemistry” 3rd Ed, Pearson/Prentice Hall publisher, ISBN 0-13-035471-6.〕 :()2+ + OH− → ()2+ + Cl− The rate law for the reaction is: : The rate law is deceptive: hydroxide serves not as a nucleophile but as a base to deprotonate the coordinated ammonia. Simultaneously with deprotonation, the halide dissociates. Water binds to the coordinatively unsaturated complex followed by proton transfer to give the hydroxy complex. The conjugate base resulting from deprotonation of the amine is rarely observed.〔Clark, C. R. and Buckingham, D. A., "Alkaline hydrolysis of ()+ and direct observation of deprotonated SN1CB intermediates", Inorganica Chimica Acta, 1997, 254, 339-343.〕 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sn1CB mechanism」の詳細全文を読む スポンサード リンク
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